Would this be your primary residence or a vacation home?
What price range?
What do you mean by "many acres"? 5? 20? 100?
What size home would you like (# of BR/BA, square footage, garage spaces, etc)
I've lived in Colorado my entire life and know the state pretty well. I've lived on Colorado's "front range" for 20+ years in Boulder County.
Good luck in your search!