I think the closest we come is the downtown area ( http://www.downtownknoxville.org/ , http://stuckinsideofknoxville.com/, http://knoxvillemarketsquare.com/). After that you would probably want to take a look at Old North Knoxville )http://en.wikipedia.org/wiki/Old_North_Knoxville), 4th & Gill (http://www.fourthandgill.org/History.html), maybe parts of Ft Sanders (http://en.wikipedia.org/wiki/Old_North_Knoxville). Another area that is up and coming is "Happy Holler" or the North Central Business District (http://www.metropulse.com/news/2012/feb/01/local-color-knoxv ).
Hope this helps. Let me know if there is anything else I can do for you.
regina.santore AT coldwellbanker dotcom
You get MORE with Regina SANTORE
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I recommend Old North Knox, 4th & Gill and downtown lofts. Are you looking to rent or buy? Ft. Sanders, or The Fort, as it popularly known here has lots of places for rent, and it is very close to campus.
Happy to assist in your search,
Realty Executives Associates
The neighborhoods directly surrounding Knoxville's downtown, and downtown itself, are the "hipster/artsy" neighborhoods: 4th and Gill, Old North Knoxville, Fort Sanders (where most students live,) Island Home Park, Edgewood/Emoriland, Oakwood/Lincoln Park, and Parkridge. But perhaps the very most "edgy" at the moment is Happy Holler, which starts at the intersection of Broadway and Central, and continues up Central Ave for a good bit. You'll find everything from yoga to tai chi there - a tea room, a concert venue, and an awesome neighborhood bar or two. Rents and mortgages in this area are still on the low side - gentrification is creeping in that direction but haven't fully arrived there yet. It's close to downtown, and even has a dedicated bike lane that will get you most of the way there. Downtown is just a mile, and UT just two miles.