We have managed a rental nearby for several years with no trouble, but neighborhoods can vary. Ask the neighbors when you do a drive-by.
San Antonio crime rates and statistics - NeighborhoodScout
This information may help you in answering the question of safety in the area.
This appears to be a nice home and will should not stay available long, it has only been on the market for 15 days. You should drive the area to determine your comfort level for the area.