Businesses tend to provide opportunity for larceny, that's typical. Vagrants are like bears, they acclimate and wander into residental areas eventually. In that neighbourhood, that is not common. Sometimes that to the fact that it is actually the much higher traffic and population that the citizens are always visual and moving so do well to police their own areas.
As for homes, at about a 2% (per 100,000) annual burglary rate in all of Winston-Salem of 300,000 people, I personally think taking sensible and somewhat passive measures regarding your own home: lights, cameras, pets, alarms, low shrubbery, strategic thorny landscaping, frustrating entry systems - storm doors, screened windows, bolt locks and the like -- and the odd hornets' nest and bear traps placed here and there (just kidding!) -- is just common sense in any neighbourhood, along with knowing your neighbours and showing general vigilance is all you need to enjoy living anywhere here.