I am new to SOMA. I moved here two weeks and live near First Street and Harrison. I walk to work everyday. It is about a 15 minute walk. In the morning, safety is not an issue at all...lots and lots of people walking to work. In the evening, I walk back around 8 or 9 pm. It is at this time that safety is on my mind. Not that many people on the street and it is pretty quiet. There have been two instance already where I have felt uncomfortable. Both cases turned out to be harmless, but nonetheless I felt less that safe. No real crime that I have seen or heard of (at least not as yet). As long as you are not walking late at night, it seems like a safe enough area.